抖阴短视频

Banner image: New MERV-13 air filters and air handler unit on the 抖阴短视频 Boulder campus.听Photo by Patrick Campbell/University of Colorado.

Humans in the 21st century spend most of their time indoors, but the air we breathe inside buildings is not regulated to the same degree as the food we eat and the water we drink. A group of 39 researchers from 14 countries, including two from 抖阴短视频听Boulder, say that needs to change to reduce disease transmission and prevent the next pandemic.

In a 听on May 14, they call for a 鈥減aradigm shift鈥� in combating airborne pathogens such as SARS-CoV-2, the virus that causes COVID-19, demanding universal recognition that respiratory infections can be prevented by improving indoor ventilation systems.

鈥淎ir can contain viruses just as water and surfaces do,鈥� said co-author Shelly Miller, professor of mechanical and environmental engineering. 鈥淲e need to understand that it's a problem and that we need to have, in our toolkit, approaches to mitigating risk and reducing the possible exposures that could happen from build-up of viruses in indoor air.鈥�

The paper comes less than two weeks after the World Health Organization (WHO) changed its website to , and 10 months after the WHO and 239 scientists (including Miller and Jose-Luis Jimenez) signed an to medical communities and governing bodies about the potential risk of airborne transmission. The researchers now call on the WHO and other governing bodies in this new article to extend its indoor air quality guidelines to include airborne pathogens and to recognize the need to control hazards of airborne transmission of respiratory infections.

Such a shift in ventilation standards should be similar in scale to the 19th century transformation that took place when cities started organizing clean water supplies and centralized sewage systems. But it would also correct a major scientific misperception that arose around the same time.

When people in London were dying of cholera in the 1850s, scientists assumed the disease was airborne. But British physician John Snow discovered that microorganisms in contaminated water were the reason. Similarly, Hungarian physician Ignaz Semmelweis showed that handwashing before delivering a baby greatly reduced postpartum infections. While these discoveries encountered great resistance in their time, scientists eventually agreed that in these cases, water and hands鈥攏ot air鈥攚ere the vector for disease.

Then in the early 20th century, American public health expert Charles Chapin erroneously attributed respiratory infections caught in close proximity to other people to large droplets produced by an infected person, which fall quickly to the ground. As a result, he stated that airborne transmission was almost impossible.听

Yet in 1945, scientist , lamenting that while we were investing in disinfecting water and keeping our food clean, we had done nothing for our indoor air, given the denial of airborne transmission. His research on measles and tuberculosis鈥攃aused by airborne pathogens鈥攃hallenged this notion in the 20th century, but didn鈥檛 break it.听

Now that the research on SARS-CoV-2 finally has brought to light that many respiratory diseases can be transmitted through the air, researchers argue that we must take action.

鈥淟et's now not waste time until the next pandemic,鈥� said said co-author Jose-Luis Jimenez, fellow in the Cooperative Institute of Research Sciences (CIRES) and professor of chemistry at 抖阴短视频 Boulder. 鈥淲e need a societal effort. When we design a building, we shouldn鈥檛 just put in the minimum amount of ventilation that's possible, but instead we should keep ongoing respiratory diseases, such as the flu, and future pandemics in mind.鈥�

The long-standing misunderstanding of the importance of airborne transmission of pathogens has left a large gap of information in how to best construct and manage building ventilation systems to mitigate the spread of disease鈥攚ith the exception of some manufacturing, research and medical facilities. Instead, buildings have focused on temperature, odor control, energy use and perceived air quality. So while there are safety guidelines for chemicals such as carbon monoxide, there are currently no guidelines, globally or in the U.S., that regulate or provide standards for mitigating bacteria or viruses in indoor air resulting from human activities.

鈥淎ir in buildings is shared air鈥攊t's not a private good, it's a public good. And we need to start treating it like that,鈥� said Miller.

Lidia Morawska, lead author on the article and director of Queensland University of Technology鈥檚 International Laboratory for Air Quality and Health, said there needs to be a shift away from the perception that we cannot afford the cost of control. She notes that the global monthly cost from COVID-19 had been conservatively estimated as $1 trillion and the cost of influenza in the U.S. alone exceeded $11.2 billion annually.

While detailed economic analysis has yet to be done, estimates suggest necessary investments in building systems may be less than 1% of the construction cost of a typical building.

Ventilation systems should also be demand-controlled to adjust for different room occupancies, and differing activities and breathing rates, such as exercising in a gym versus sitting in a movie theatre, according to Morawska. For spaces that cannot improve ventilation to an appropriate level for the use of the space, she said air filtration and disinfection will be needed.

Because buildings consume over one-third of energy globally, much from heating or cooling outdoor air as it is brought indoors, it would be useful to design a 鈥減andemic mode,鈥� that would allow for buildings to only use more energy when necessary, said Jimenez.

The researchers also call for national comprehensive indoor air quality (IAQ) standards to be developed and enforced by all countries, and for this information to be available to the public.听

For this to happen, however, many more than scientists will need to understand its importance.

鈥淚 think there is a certain amount of demand that needs to start coming from the consumer and from the person who works in these indoor spaces in order to push change,鈥� said Miller.听